The main interest of this research focuses on the development of a stable and believable method to analyze folates in plant. Folates are very important to human health and deficiency can cause coronary heart deseases and stroke, CVD, Neural Tube Defects (NTDs), cancer and birth defects.The source of folates for humans is mainly from plant food because humans canít synthesize folate. Getting a stable and believable method to analyze folate is the first and important step when we try to control and increase the content of folate in the plant. Our research is challenging the following difficulties:
To overcome these challenges, chromatographic techniques such as HPLC-DAD, HPLC-FD (fluorescence detector), and HPLC-MS will be exploited.
Figure: Chemical structures of various folates:
(By Guo Fang Zhang)